Anime Vanguards: Best Unit Tier List (Update 4.5)

Aaron Rabaya
9 Min Read

If you’re looking to get the edge in your gameplay in Update 4, you’ve come to the right place. In this Anime Vanguards tier list, I will break down the best units available in the game, helping you figure out which ones are worth your time and resources. Whether you’re just starting out or looking to optimize your team, I’ve got you covered. From the unstoppable S-tier legends to the reliable support units, we’ll help you navigate the current meta and build a squad that can take on any mode!

Best Unit Tier List (Update 4.5)

The game is always changing, and with new characters dropping, the rankings can flip pretty quickly. With the arrival of Update 4.5, I’m here to break down the strengths and weaknesses of each unit so you can put together the best team possible. Whether you’re all about dishing out damage, controlling the battlefield, or supporting your units, this list will help you figure out which units to grab and level up as you dive into Story and Infinite modes.

Before we dive in, keep in mind that every unit has its own strengths, and rankings can be situational. Some units shine in specific modes, while others are more universally strong. This tier list focuses primarily on the recent changes to a character within the update. Other units may stay the same as time goes on. Here’s how I’ve structured this tier list:

  • S-Tier – The absolute best units in the game. These units dominate in multiple game modes and should be prioritized for investment.
  • A+ Tier – Very strong units that perform exceptionally well but might require specific setups or have minor drawbacks compared to S-Tier units.
  • Great Supports – Essential support units that can significantly enhance your team’s effectiveness, whether through buffs, debuffs, or utility.
  • A-Tier – Solid units that hold their own in battle. They might not be as broken as S or A+ tier units, but they are still viable choices.
  • Good Supports – Situationally strong support units. They may not be meta-defining but can be valuable in specific team compositions.
  • B-Tier – Decent units that can be useful for newer players but start to fall off in higher-level content.
  • C-Tier – Generally outclassed units that struggle to keep up with stronger options. Use them if necessary, but don’t invest too heavily.
Tier List Update 4.5 in Anime Vanguards

S-Tier (Best of the Best!)

You should aim to get every unit in this tier—no debate.

  • Song Jin-Wu & IgrosOne of the two strongest units in the game, featuring insane damage output, strong passives, and excellent survivability.
  • Bogita – The only unit tied with Song Jin-Wu & Igros for #1, boasting top-tier burst damage and AoE. Both are really broken as considered by most players as of the update.
  • Ichigo – After receiving an updated passive, Ichigo has now become a staple DPS in high-level play!
  • Gojo – Despite being introduced in Update 1, Gojo is still meta, thanks to his high DPS and freeze ability.
  • Eizan (Aura) – Eisen easily kills enemies when they walk into his range, making him an absolute monster in PvE.
  • Regnaw – This unit has insane damage scaling that makes him a really good DPS option.
  • Ram & Rem – These twins are full AoE and deal massive damage, together they completely outclass Igris as a damage dealer.
  • Yomomata – A meta-defining burn unit who buffs all burn-based characters, making him crucial for burn teams.
  • Yehowach – A meta DPS unit capable of supporting high-tier strategies with his powerful abilities.
  • Saber – The King of Knights maintains her status in Update 4.5 as a top-tier DPS unit thanks to her powerful attacks and overall reliability.

A+ Tier

I added this tier because I felt S-tier got a bit too crowded. Every unit here is worth getting.

  • Choy Jong-EnA top-tier burn unit that deals 50% extra burn damage and increases burn tick rate, making burn-focused teams much stronger.
  • Yuruicha: Another great high-speed unit with great AoE and mobility.
  • Saber (Black Tyrant):  Make no mistake, she is still a powerful version of Saber that provides strong single-target and AoE attacks.
  • Cu Chulainn (Lancer): This high-attack speed unit has excellent team synergy and is capable of keeping up with the meta characters.
  • Gilgamesh: The King of Heroes remains one of the strongest picks but only reaches his full potential when surrounded by Fate units (like Saber and Ishtar).
  • Dave: A high DPS unit that benefits from Luce’s support. He works well in teams focused on pure damage output.
  • Friran – This sub-dps can generate buffs like 50% attack and range but is very inconsistent, making her situationally powerful.
A+ Tier in Anime Vanguards: Best Unit Tier List (Update 4.5)

Great Supports

If a unit is in this tier, you should get them—no question. There’s no specific order here since they all serve different purposes.

  • Luce: The best support in the game right now. This is all thanks to her ability to remove enemy resistance completely.
  • Gazelle (Zombie): Boosts summon units by 50%, making her essential for teams that rely on summoned allies.
  • Rengoku: A burn support that increases the effectiveness of burn teams, making burn comps significantly stronger.
  • Chaos (Blood Curse): He a strong bleed-support unit that increases the damage potential of all bleed-based units.
  • Sosuke: A stun-based unit that is useful for leaderboard strategies, but in my opinion, not a top-tier damage dealer.
Great Supports in (UPDATE) Anime Vanguards: Best Unit Tier List (Update 4)

A-Tier

Units in this tier are otherwise great options even with better choices. They do their jobs just fine and offer a ton of value in Update 4.5

  • Vogita Super: Still a great unit to choose for DPS, but sadly, he has been slightly power-crept by newer units.
  • Tengon: He is a full AoE unit, but his damage output has been outclassed by newer characters. Still a good choice.
  • Medusa:  A strong crowd-control unit that can petrify enemies, making her very effective for Infinite Mode.
  • Kiskae: A  very solid burn DPS unit, but not as strong as other burn-focused units like Yamamoto and Choy Jong-En.
  • Tuji: One of the best shield-breaker units, he allows teams to counter overshield enemies effectively.
A Tier in (UPDATE) Anime Vanguards: Best Unit Tier List (Update 4)

Good Supports

Being in the “Good Supports” tier doesn’t mean a unit isn’t meta. Instead, it means they shine in specific situations or as alternatives if you lack stronger meta units.

  • Sokura: She is a corruption buffer that increases enemy damage taken, but weaker than Luce).
  • Haruka Rin: This support character is more of a budget unit. While viable,  her buffs are weaker compared to stronger options like Soburo or Luce.
  • Alligator: Alligator is a decent slow-support unit, but outclassed by stronger CC-focused characters.
Good Supports in Anime Vanguards

Also, I don’t rank supports within their tier because they serve different functions. Instead, I recommend prioritizing high-tier supports first and grabbing the others afterward. Pro players often collect all of them to cover niche situations—like Rengoku, who buffs burn damage but isn’t universally meta.

Wrap-Up

The meta in Anime Vanguards is always evolving, and as new units drop or balance changes hit, rankings will shift. If your favorite unit isn’t at the top, don’t stress too much—team synergy and strategy can make a huge difference. Keep experimenting, adapt to the changes, and most importantly, have fun with the game! Got thoughts on the rankings? Think a unit deserves to move up or down? Drop a comment and let’s talk about it!

Aaron is an up and coming writer who adores coop-based videogames. He enjoys the thrill of teamwork while sharing a laugh with his friends. He is also a fan of playing older titles like Fallout or the Batman Arkham series, but never refuses to try out new games. Especially games where he could hop on with others. To him, the best experience is an experience shared with others.
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