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How to Get & Use Potent Blood in Diablo 4

Only the blood can allow you to reach the full potential of your power!

Diablo 4 continues to provide interesting updates and seasonal events that has fans continuing to play the game. This includes the latest Blood Harvest seasonal event that has added Vampiric themed quests, monsters and content. One important item that plays a vital role in this seasonal event is Potent Blood.

However, it is not immediately clear how you are supposed to obtain it and make use of it. So, in this guide, we will show you how to get and use Potent Blood in Diablo 4. In this way, you can start farming this precious item and start boosting your Vampiric Power for the event! Let’s dive in!

How to Get & Use Potent Blood in Diablo 4

Potent Blood is basically a brand new currency for the Blood Harvest seasonal event. Potent Blood can be used to upgrade the new Vampiric Powers that are also part of the event.

So, it is a precious resource that can allow you to fulfill your character’s true potential and make them powerful.

Potent Blood in Material Tab in Diablo 4.

There are a number of ways that you can get Potent Blood. You will come across these methods by participating in the Blood Harvest Event.

Here is the location where the event and quests can be found. We recommend that you start out by following the seasonal questline to start getting them.

Blood Harvest quest on map in Diablo 4.

As you progress through the event, you will come across Vampiric Monsters. Defeating these Monsters will lead to Potent Blood dropping, and you can pick them up.

You can also open Seeker Caches and come across Blood Seekers that you can defeat for Potent Blood too. Moreover, you may also come across Chests that you can open to obtain Potent Blood.

Defeating Vampiric Monsters for Potent Blood drops in Diablo 4.

Another method of getting Potent Blood is by progressing the Hunters’ Acclaim Board. This can be found in the area where you start the Blood Harvest questline.

The Hunters’ Acclaim provides you with Reward Caches as you progress through it by killing monsters and gaining XP.

You can think of the Hunters’ Acclaim like a battle pass which basically rewards you for progressing through the Seasonal Event.

Hunters' Acclaim providing Potent Blood in Diablo 4.

Once you have accumulated enough Potent Blood, you can move on to the step of upgrading your Vampiric Powers.

You can keep track of your Potent Blood by going into the Character Screen and going into the Materials tab.

You can open the Vampiric Powers interface in the Seasonal tab of your Inventory. When you click on it, you will find an Upgrade Tree where you can unlock new Powers or upgrade existing ones up to a maximum of Level 3.

Vampiric Powers Upgrade Tree in Diablo 4.

Unlocking and upgrading these powers will allow your character to unleash some really devastating powers. It will also make the Seasonal Event more fun, allowing you to use your Vampiric abilities in new and fun ways!

That’s everything you need to know about getting and using Potent Blood in Diablo 4. We have provided multiple ways to get Potent Blood and you can choose whichever method you want to farm. Be sure to make the most of this Seasonal Event before it expires!

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